Epigenetics refers to external modifications made to DNA and proteins associated with DNA. These modifications turn genes on or off but do not affect the DNA sequence. Epigenetic regulation is an important part of normal cell development and cell fate determination but when dysregulation of epigenetic mechanisms occur the results can be detrimental. The dysregulation of these epigenetic mechanisms may be in response to internal and external, or environmental, factors.
|DNA molecule that is methylated on both strands on cytosine|
by Christoph Bock