|Transmission electron micrograph of the bacteriophage Qβ|
attached to sex pilus of the bacterium Escherichia coli
by Dr Graham Beards
The results showed that phages from antibiotic treated animals did indeed carry a higher number of genes for drug-resistance. Furthermore, they were able to transfer the resistance genes to bacteria. When phages isolated from antibiotic treated mice were combined with bacteria from untreated mice the researchers saw an increase in antibiotic resistance that was 2 to 3 times what is normally seen.
These results open the door for new avenues of treatment that target the phage rather than the bacteria. Assessing viral susceptibility to drug treatment is a potential application that could employ the NEPHELOstar Plus from BMG LABTECH. Since a nephelometer detects insoluble particles with high sensitivity using a laser, the NEPHELOstar Plus has the potential to be able to monitor changes in the amount of virus in a sample and to do so in a microplate format.
For more information on the NEPHELOstar Plus and other microplate readers from BMG LABTECH please visit our website: www.bmglabtech.com