Wednesday, March 14, 2012

Fun Fact: RNA Drug Targets for Muscular Dystrophy

For the first time, a series of small molecule have been rationally designed to bind to an RNA structure that is known to be involved in muscular dystrophy. The small molecules were found by querying a defective RNA motif against a database of small molecules. The subsequent ‘hits’ were customized and were found to improve protein splicing defects in cell and animal models. These RNA binding compounds may lead to a novel drug treatment for adult onset of muscular dystrophy. http://www.sciencedaily.com/releases/2012/02/120222204337.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29&utm_content=Google+Feedfetcher

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