Thursday, August 18, 2011

Inside Applications: Reaction optimization by parallel kinetic studies

Spectral changesPointKinetic studies on the metallation of porphyrin
PointChanges in the absorbance spectra monitored with the FLUOstar Omega
The yields of chemical reactions may vary considerably with parameters such as solvent, catalyst, temperature and reaction time. Here we have monitored the metallation of a porphyrin with zinc as a function of solvent. The porphyrin starting material and product are both highly coloured and the reaction proceeds with a colour change. Monitoring is ideally suited to the BMG LABTECH FLUOstar Omega microplate reader due to its ability to acquire a full UV-visible absorbance spectrum of each well in less than one second. This and other absorbance based assays can also be performed on BMG LABTECH's new absorbance microplate, cuvette and low-volume reader SPECTROstar Nano.

1 comment:

  1. This is very useful for folks who have done this in many cuvettes.

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